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GLYCOLYSIS SIMPLIFIED

Updated: Nov 8, 2023

GLYCOLYSIS SIMPLIFIED

source: ZMEScience

Some of my students struggle with cellular respiration so I decided to write the most simplified explanation for cellular respiration. This particular post covers the 1st part of cellular respiration called, "Glycolysis."

  • What is Cellular Respiration? process where macromolecules are used to produce ATP in the presence of oxygen

  • What is ATP? short for Adenosine Triphosphate, which is the primary energy used by cell

  • So why is cellular respiration necessary? it produces energy for our cells so they can survive

GLYCOLYSIS (Location: cytoplasm)

What is glycolysis? breakdown of glucose that allows transfer of energy into high-energy electron carriers and ATP


1st step

Glucose is converted to two G3P (glyceraldehyde 3-phosphate) after 5 reactions (rxn 1-5). 2 ATP are used up.

Glucose --> 2 G3P






2nd step

G3P is converted to 3-PG (3-phosphoglycerate) after 2 reactions (rxn 6-7) and this reaction occurs twice because two G3P molecules were produced from previous step. Each reaction produces 1 ATP + 1 NADH, meaning we have 2 ATP + 2 NADH after two rounds of this reaction.

2 G3P --> 2 3-PG

ATP count so far is "0" because we had -2 ATP from previous step



3rd step

3-PG is converted to pyruvate after 3 reactions (rxn 8-10). Likewise, this reaction occurs twice because we previously had two 3-PG molecules produced. 2 ATP are produced.

2 3-PG --> 2 pyruvate






SUMMARY

Glycolysis produces 2 pyruvate, 2ATP & 2NADH


Steps 1-3 of glycolysis

Glucose --> 2 G3P (-2ATP)
2 G3P --> 2 3-PG (+2ATP, +2NADH)
2 3-PG --> 2 pyruvate (+2ATP)

This is glycolysis summed up in one reaction

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